Genetic diversity of Listeria monocytogenes from seafood products, its processing environment, and clinical origin in the Western Cape, South Africa using whole genome sequencing
Whole genome sequencing was used to compare Listeria monocytogenes from seafood and food processing environments with clinical isolates from the Western Cape. The collection comprised fish and seafood product isolates, processing-environment isolates, and human clinical isolates. Clinical isolates clustered in lineage I, whereas most seafood and processing-environment isolates belonged to lineage II. A substantial share […]
Evaluating Procedure-Linked Risk Determinants in Trichinella spp. Inspection under a Quality Management System in Southern Spain
This study analyzed how deviations from standard procedures within a quality management system (QMS) influence risk levels during Trichinella spp. meat inspections in southern Spain. Audits of 18 satellite laboratories over six years revealed that procedural deviations—especially those related to technical execution and trial information (e.g., incorrect tests, calculations, or deviations from protocols)—were associated with […]
Another potential zoonotic threat? Herpes B virus in the spotlight
This Perspective highlights renewed public health concern following the first documented human case of Herpes B virus (Cercopithecine herpesvirus 1) infection in Hong Kong, where a macaque-inflicted scratch caused severe neurological illness. The virus typically resides asymptomatically in macaques—especially species like Macaca mulatta, M. fascicularis, and pig-tailed macaques—but can lead to fatal encephalomyelitis in humans, […]
One Health implementation: A systematic scoping review using the Quadripartite One Health Joint Plan of Action
One Health (OH) emphasizes the links between human, animal, and environmental health, and this review assessed how OH is being implemented globally, regionally, nationally, and locally using the OH Joint Plan of Action (OH JPA). The review applied the OH JPA Theory of Change to map initiatives across six action tracks, drawing on studies from […]
Appraising Nigeria’s approach to combating antimicrobial resistance
This short communication provides a qualitative assessment of Nigeria’s efforts against antimicrobial resistance (AMR) following the implementation of the 2017–2022 National Action Plan (NAP). It highlights notable progress in public awareness campaigns, One Health-inclusive surveillance, infection prevention and control (IPC), antimicrobial stewardship, and research support. These initiatives stem from the establishment of the Antimicrobial Resistance […]
Another potential zoonotic threat? Herpes B virus in the spotlight
This Perspective highlights renewed public health concern following the first documented human case of Herpes B virus (Cercopithecine herpesvirus 1) infection in Hong Kong, where a macaque-inflicted scratch caused severe neurological illness. The virus typically resides asymptomatically in macaques—especially species like Macaca mulatta, M. fascicularis, and pig-tailed macaques—but can lead to fatal encephalomyelitis in humans, […]
How dopamine tunes parvalbumin interneurons in the hippocampus: new experimental observations in Alzheimer’s disease
In Alzheimer’s disease (AD) mouse models (Tg2576), degeneration of ventral tegmental area (VTA) dopaminergic neurons impairs hippocampal dopaminergic innervation, leading to dysfunction of parvalbumin-expressing interneurons (PV-INs). These PV-INs display reduced firing, diminished spontaneous inhibitory postsynaptic currents (sIPSCs), decreased gamma oscillations, and lowered nuclear levels of p-CREB and c-Fos, alongside fewer PV-INs and attenuated perineuronal nets. […]
African countries from the Pasteur Network reexamine their syndromic sentinel surveillance system associated with household contact within the AFROSCREEN program
This perspective outlines the deliberations of Pasteur Network teams from Niger, Central African Republic, Cameroon, Senegal, and Madagascar, convened in Cameroon to inform pilot syndromic sentinel surveillance in Africa. Leveraging lessons from the COVID-19 pandemic, the group proposed combining influenza-based syndromic and biological surveillance with the enhanced sequencing capacity provided by the AFROSCREEN initiative. The […]
Automated dairy cattle lameness detection utilizing the power of artificial intelligence; current status quo and future research opportunities
This review synthesizes automated AI-based approaches to dairy cattle lameness detection across accelerometers, load cells and weighing platforms, acoustic and radar sensors, and computer vision. Reported systems generally classify lame versus non-lame cows with adequate reliability, but performance varies by sensing modality, chosen features, and the ground truth used, which is most often visual mobility […]
The Regulation of Cerebral Lymphatic Drainage in the Transverse Sinus Region of the Mouse Brain
This research elucidates the role of norepinephrine (NE) in modulating cerebral lymphatic drainage. NE administration was found to rapidly reduce glymphatic influx while enhancing meningeal lymphatic clearance, particularly within the transverse sinus (TS) region. Inhibiting NE simultaneously enhanced both glymphatic and dorsal meningeal lymphatic drainage, pinpointing the TS as the primary regulatory hub within the […]